维生素C片研磨后局部涂抹治疗口腔溃疡的临床观察
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篇名: | 维生素C片研磨后局部涂抹治疗口腔溃疡的临床观察 |
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摘要: | 目的:观察维生素C片研磨后局部涂抹治疗口腔溃疡的临床疗效及安全性。方法:选取2014年2月-2016年2月我院口腔溃疡患者286例,按随机数字表法分为对照组和治疗组,各143例。对照组患者采用桂林西瓜霜局部治疗,每日2~3次;治疗组患者采用维生素C片研磨成粉涂抹患处治疗,每日2~3次。观察两组患者临床疗效、溃疡症状消失时间、不良反应发生率、溃疡复发率和治疗满意度。结果:治疗组患者临床总有效率为96.5%,显著高于对照组的80.4%,差异有统计学意义(P<0.05)。治疗组患者溃疡症状消失时间为(2.37±0.89) d,显著短于对照组的(4.12±1.33) d;治疗组患者溃疡复发率为3.5%,显著低于对照组的8.4%;治疗组患者治疗满意度为90.9%,显著高于对照组的79.7%,差异均有统计学意义(P<0.05)。两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论:维生素C片研磨成粉末局部涂抹治疗口腔溃疡疗效显著,能明显缩短溃疡症状消失时间,降低复发率,提高治疗满意度,且安全性较好。 |
ABSTRACT: | OBJECTIVE: To observe the clinical efficacy and safety of Vitamin C tablets after grinding for local use in the treatment of oral ulcer. METHODS: Two hundved and eighty-six cases of oral ulcer in our hospital during Feb. 2014-Fed. 2016 were selected and divided into treatment group and control group according to random number tabel, with 143 cases in each group. Control group was given Guilin watermellon frost, 2-3 tirnes a day; treatment group was given Vitamin C tablets powder for local use, 2-3 tirnes a day. Clinical efficacy, the time of ulcer disappearance, the incidence of ADR, recurrence rate of ulcer, treatment satisfactory degree were observed in 2 groups. RESULTS: Total response rate of treatment group was 96.5%, which was significantly higher than 80.4% of control group, with statistical significance (P<0.05). The time of ulcer disappearance was (2.37±0.89) d in treatment group, which was significantly shorter than (4.12±1.33) d of control group; recurrence rate of ulcer was 3.5%, which was significantly lower than 8.4% of control group; treatment satisfactory degree was 90.9%, which was significantly higher than 79.7% of control group, with statistical significance (P<0.05). There was no statistical significance in the incidence of ADR between 2 groups (P>0.05). CONCLUSIONS: Vitamin C tablets after grinding for local use has obvious effect on oral ulcer, significantly shortens the time of ulcer disappearance, reduces recurrence rate, and improves treatment satisfactory degree with good safety. |
期刊: | 2017年第28卷第8期 |
作者: | 黄嘉,李泽贵,彭涛,罗凯颖 |
AUTHORS: | HUANG Jia,LI Zegui,PENG Tao,LUO Kaiying |
关键字: | 维生素C片;口腔溃疡;临床疗效 |
KEYWORDS: | Vitamin?C?tablet;?Oral?ulcer;?Clinical efficacy |
阅读数: | 1030 次 |
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