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基于患者异质性的仿制药一致性评价补贴策略研究
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| 篇名： | 基于患者异质性的仿制药一致性评价补贴策略研究 |
| TITLE： | |
| 摘要： | 目的：考虑患者对仿制药认可度的异质性，建立制药企业与政府之间的博弈决策模型，为政府对仿制药一致性评价补贴政策的制订提供决策依据。方法：基于患者异质性分别建立无政府补贴、补贴仿制药企业和补贴患者3种补贴策略下的两阶段博弈模型，对比分析3种补贴策略下患者异质性对制药企业及政府决策的影响。结果：患者对仿制药认可度的增大，仿制药的市场需求也随之增大；仿制药的市场价格与政府补贴的关系在补贴仿制药企业时呈负相关，在补贴消费者时呈正相关。结论：政府补贴可以增进消费者剩余和社会福利，并且政府采取补贴患者和补贴仿制药企业所产生的社会效益相同。政府在达到相同社会福利的前提下，可采取补贴仿制药企业的策略降低政府支出；采取补贴患者的形式鼓励仿制药企业进行仿制药一致性评价工作的开展。 |
| ABSTRACT： | OBJECTIVE： To consider the heterogeneity of patients’ acceptance of generic drugs， to establish a game decision-making model between pharmaceutical enterprises and the government， and to provide decision-making basis for the government to formulate subsidy policies for the generic drug conformance assessment. METHODS： A two-stage game model was established on the basis of patient heterogeneity under three subsidy strategies： the government does not subsidize， subsidize generic drug companies and subsidize patients. Effects of patient heterogeneity on the decision-making of pharmaceutical enterprises and the government were compared and analyzed under three subsidy strategies. RESULTS： With the increase of patients’ recognition of generic drugs， the market demand for generic drugs is also increasing. The relationship between the market price of generic drugs and government subsidies was negatively correlated when subsidies were given to generic pharmaceutical enterprises， and positively correlated when subsidies were given to consumers. CONCLUSIONS： Government subsidies can increase consumer surplus and social welfare， and the social benefits of government subsidies for patients and generic pharmaceutical enterprises are the same. On the premise of achieving the same social welfare， the government can adopt the strategy of subsidizing generic pharmaceutical enterprises to reduce government expenditure. The form of subsidizing patients is adopted to encourage the generic pharmaceutical enterprises to carry out the generic consistency evaluation. |
| 期刊： | 2019年第30卷第23期 |
| 作者： | 刘玉颖，陈宇，黄哲 |
| AUTHORS： | LIU Yuying，CHEN Yu，HUANG Zhe |
| 关键字： | 患者异质性；仿制药；一致性评价；政府补贴；博弈模型 |
| KEYWORDS： | Patient heterogeneity； Generic drugs； Conformance assessment； Government subsidies； Game model |
| 阅读数： | 334 次 |
| 本月下载数： | 5 次 |
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