目的：为多囊卵巢综合征治疗药物的合理使用提供参考。方法：统计我院2013 年1－12 月多囊卵巢综合征治疗药物的

销售金额和用药频度（DDDs）等，并进行排序，依据相应规范和药品说明书等资料分析处方合理性。结果：多囊卵巢综合征处方

共1 551 张，涉及76 种药物，总销售金额为181 072.90 元；药品种类以激素相关药物（处方频次占比81.37％，销售金额占比

73.51％）和中成药（处方频次占比15.41％，销售金额占比19.43％）为主。激素相关药物DDDs排名前5 位的是炔雌醇环丙孕酮片、

盐酸二甲双胍肠溶片、黄体酮胶丸、地屈孕酮片和黄体酮软胶囊；中成药DDDs排名前5 位的是坤泰胶囊、右归胶囊、还少胶囊、加

味逍遥胶囊和女金胶囊。处方中单药使用率为72.08％；不合理用药处方比例为1.69％。结论：我院多囊卵巢综合征用药总体合

理。个别处方存在不合理情况，主要表现在临床诊断不全和用法用量不合理，药师需加强对处方的审查与干预。

OBJECTIVE：To provide reference for rational use of polycystic ovary syndrome（PCOS）drugs. METHODS：The

utilization of PCOS drugs in our hospital during Jan.-Dec. 2013 were analyzed in respects of consumption sum，DDDs，sorting and

so on. The rationality of prescription was analyzed according to guidelines and drug package inserts and so on. RESULTS：There

were 1 551 prescriptions，involving 76 kinds of drugs，and their total consumption sum was 181 072.90 yuan. Main types of drugs

were hormone related drugs（accounting for 81.37％ of prescription frequency，73.51％ of consumption sum）and Chinese patent

medicine （accounting for 15.41％ of prescription frequency，19.43％ of consumption sum）. Top 5 hormone drugs in the list of

DDDs were Ethinylestradiol and Cyproterone acetate tablets，Metformin hydrochloride enteric-coated tablets，Progesterone soft capsule，

Dydrogesterone tablets and Progesterone soft capsules. Top 5 Chinese patent medicines in the list of DDDs were Kuntai capsule，

Yougui capsule，Huanshao capsule，Jiawei xiaoyao capsule and Nvjin capsule. Single drug accounted for 72.08％ in prescription.

The proportion of irrational drug use was 1.69％. CONCLUSIONS：The application of drug in patients with PCOS is reasonable

generally. Some prescriptions are unreasonable，mainly manifesting as incomplete clinical diagnosis，irrational usage and dosage.

Pharmacists should strengthen prescription verification and intervention.