目的：了解我院慢性鼻-鼻窦炎（CRS）鼻腔分泌物的细菌学特征，并对其开展药敏试验，为临床治疗提供理论依据。方

法：选择行鼻内镜手术的CRS患者共87 例，对其鼻腔分泌物进行细菌培养，采用全自动微生物分析仪进行鉴定，用纸片扩散法进

行体外药敏试验。结果：87 例患者中，有77 例检出细菌，阳性率为88.5％；检出细菌112 株，其中需氧菌81 株、厌氧菌31 株，以金黄

色葡萄球菌最为常见（20.54％）；体外抗菌药物敏感率最高的为莫西沙星（89.29％），其次为环丙沙星、万古霉素（均为87.50％）。

结论：我院CRS患者鼻腔分泌物细菌检出阳性率高，以需氧菌感染为主，临床应根据药敏试验结果针对性使用抗菌药物治疗。

OBJECTIVE：To investigate the bacteriological characteristics of nasal secretions of chronic rhinosinusitis（CRS）in

our hospital，and conduct drug sensitivity test in order to provide theoretic reference for clinical treatment. METHODS：87 CRS

patients underwent nasal endoscopic surgery were selected and the nasal secretions of patients were taken for bacterial culture.

Automatic microbial analyzer was used to identify the bacteriological characteristics，and disk diffusion test was adopted for drug

sensitivity test. RESULTS：Of 87 patients，bacterial strains were detected from 77 cases of nasal secretions，with positive rate of

88.5％ . 112 strains were detected，including 81 strains of aerobic bacterium and 31 strains of anaerobic bacterium，and the most

common bacterium were Staphylococcus aureus （20.54％）. Antibiotics with the highest sensitivity was moxifloxacin （89.29％），

followed by ciprofloxacin（87.50％），vancomycin（87.50％）. CONCLUSIONS：The bacterial in nasal secretions of CRS patients has

high positive detection rate and mainly are aerobic bacterium. Antibiotics should be used rationally according to the results of drug

sensitivity test.