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基于CiteSpace的国内外妊娠期用药研究文献分析
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| 篇名： | 基于CiteSpace的国内外妊娠期用药研究文献分析 |
| TITLE： | Literature Analysis of Domestic and Foreign Drug Use in Pregnancy Period Based on CiteSpace |
| 摘要： | 目的：为提高妊娠期患者安全用药水平提供参考。方法：分别以中国知网和WebofScience为国内、国外文献检索平台，检索与妊娠期用药的相关文献，利用检索平台提供的文献分析功能并结合CiteSpace5.5R2软件对妊娠期用药的相关文献进行分析，对收集到的国内外文献的年度发文量、作者、机构和国家、关键词共现、文献共被引分析的数据进行可视化处理，分析其研究热点。结果：共纳入国外文献38946篇、国内文献698篇，国内文献明显少于国外文献；国外妊娠期用药的文献发文量呈逐年增加趋势，但国内文献的发文量波动较大且上升缓慢。国外各机构、学者合作密切，构建了密切的合作网络，尤其以美国最多；而国内文献的作者团队整体较为分散，研究者之间的合作也较少，尚未形成大的合作团队。国外被引频次最多的文献以随机对照研究和大型队列研究为主，关键词“Risk”出现的频率最高，表明其重点关注妊娠期用药对妊娠结局和子代的影响，此外妊娠期使用抗癫痫药、抗抑郁药、阿片类药物对妊娠结局和儿童发育的影响也是目前国外研究的一个热点；而国内研究缺乏大样本、高质量的临床研究，国内文献高频关键词包括“胎儿“”妊娠期高血压”等，其研究内容以妊娠期合并疾病的治疗为主，对妊娠结局关注不足。结论：妊娠期用药的研究日趋受到学者重视；国内学者应加强与国际的合作交流，借鉴国外团队的优秀经验，建立专门的妊娠期用药研究团队；相关部门应尽快出台措施，扶持各医疗机构和药品生产研发企业做好妊娠用药登记，尽快建立我国妊娠期用药的数据库，保障妊娠期患者的用药安全。 |
| ABSTRACT： | OBJECTIVE：To provide reference for improving safe drug use in pregnant women. METHODS ：Retrieved from as domestic and foreign literature retrieval platforms as CNKI and Web of Science ，the literatures about drug use in pregnancy period were collected and analyzed by using the literature analysis function provided by the retrieval platform and CiteSpace 5.5R2 software. The collected data of annual volume ，author，organization，keyword co-occurrence and literature co-citation analysis of domestic and foreign literatures are visualized ，and the research focus was analyzed. RESULTS ：A total of 38 946 foreign literatures and 698 domestic literatures were included ，and domestic literatures were less than foreign literatures ；the literature volume on pregnancy drug use were increasing year by year at abroad，but the volume of domestic literatures fluctuates greatly and increased slowly. Foreign institutions and scholars worked closely together ，and built a close cooperation network ，especially in the United States. However ，the author team of domestic research was relatively scattered as a whole ，and the cooperation between researchers was less ，so a large cooperation team had not yet been formed. The most frequently cited literatures in the world were randomized controlled studies and large-scale cohort studies，the keyword “Risk”appears most frequently ，indicating that it focuses on the effects of pregnancy medication on pregnancy outcomes and offspring. The effects of antiepileptic drugs ，antidepressants and opioids used in pregnancy on pregnancy outcomes and child development were currently a research hotspot abroad. However ，there was a lack of large-scale sample and high-quality clinical research in China ，high-frequently keywords in domestic literatures indude “fetus”“hypertension in pregnancy ”etc.，which focused on the treatment of combined diseases in pregnancy and paid little attention to the long-term effects of medication in pregnancy. CONCLUSIONS：More and more attention had been paid to the study of drug use in pregnancy period. Domestic research needs to seize the international cooperation communication ，learns from the excellent experience of foreign research team ，and establishes domestic specific pregnancy medication research team. Relevant departments should introduce measures as soon as possible ，support medical institutions and drug production and developmententerprises to do a good job in the registration of pregnancy medication，establish the database of pregnancy medication inChina as soon as possible ，and improve the medication safety of pregnant patients. |
| 期刊： | 2020年第31卷第10期 |
| 作者： | 闫园园，唐红波，阴赪宏，冯欣，赵志刚 |
| AUTHORS： | YAN Yuanyuan，TANG Hongbo，YIN Chenghong，FENG Xin，ZHAO Zhigang |
| 关键字： | 妊娠期；研究现状；CiteSpace；用药安全 |
| KEYWORDS： | Pregnancy；Research status ；CiteSpace；Safety of drug use |
| 阅读数： | 513 次 |
| 本月下载数： | 9 次 |
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