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AHP-TOPSIS法量化评价我院骨科Ⅰ类切口手术预防性使用抗菌药物的合理性
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| 篇名： | AHP-TOPSIS法量化评价我院骨科Ⅰ类切口手术预防性使用抗菌药物的合理性 |
| TITLE： | Quantitative Evaluation of the Prophylactic Use Rationality of Antibiotics in Orthopedic Type Ⅰ Incision Surgery of Our Hospital Based on AHP-TOPSIS |
| 摘要： | 目的：建立骨科Ⅰ类切口手术预防性使用抗菌药物的量化评价体系，为科学评价该类手术抗菌药物预防使用的合理性提供参考。方法：以《抗菌药物临床用指导原则（2015版）》、相关药品说明书、相关指南与文献为依据，由相关科室专家共同商讨制定骨科Ⅰ类切口手术预防性使用抗菌药物合理性评价标准。采用层次分析法（AHP）对评价标准的各项指标进行赋权，并运用加权逼近理想解排序法（TOPSIS）对北京大学人民医院2019年9月1－30日的3个骨科科室的120例Ⅰ类切口手术患者的归档病例进行回顾性分析和合理性评价。结果：建立的评价体系包括4个一级指标（用药指征、用法用量、给药时机、其他因素）和12个二级指标，二级指标中权重占比较高的有适应证、药品选择及术前给药时机（权重分别为0.209、0.140、0.117）。在纳入的120份病例中，用药合理的占30.83％，基本合理的占47.50％，不合理的占21.67％。采用AHP-TOPSIS法所得评价结果与实际情况相符。结论：基于AHP-TOPSIS法建立的Ⅰ类切口手术预防使用抗菌药物合理性评价的方法，可将多个指标结合起来对用药合理性进行量化评估。该方法切实可行、操作性强、评价结果可量化，具有较广泛的适用范围。 |
| ABSTRACT： | OBJECTIVE：To establish quantitative e valuation system of the prophylactic use of antibiotics in orthopedic type Ⅰ incision surgery ，and to provide reference for evaluating the rational prevention use of antibiotics in this type surgery scientifically. METHODS：Based on the Guidelines of Clinical Use of Antimicrobial Agents （2015 edition），drug instructions ，related guidelines and references ，experts from relevant departments jointly discussed and formulated the evaluation criteria for the rationality of the use of antibiotics in type Ⅰ incision in orthopedic surgery. AHP method was used to assign the weights for various indexes of evaluation criteria ；TOPSIS method was used to retrospectively analyze and evaluate the rationality of 120 cases of type Ⅰ incision surgery from 3 orthopedic departments in Peking University People ’s Hospital during Sept. 1st-30th，2019. RESULTS ：Established evaluation system included 4 primary indicators （medication indication ，usage and dosage ，medication timing ，other factors ）and 12 secondary indicators. Among the secondary indicators ，indications，drug selection and timing of preoperative administration were the most important （weights were 0.209，0.140，0.117）. Among 120 cases，30.83％ of drug use were reasonable ，47.50％ were basically reasonable and 21.67％ were unreasonable. Evaluation results obtained by AHP-TOPSIS were consistent with the actual situation. CONCLUSIONS ：The rationality evaluation method of prophylactic use of antibiotics in type Ⅰ incision surgery based on AHP-TOPSIS method can quantitatively evaluate the rationality of drug use by combining multiple indicators. The method is feasible ，operable，and the evaluation results can be quantified ，which has a wide range of application. |
| 期刊： | 2021年第32卷第05期 |
| 作者： | 刘一，梁馨玉，宋佳伟，刘悦，胡蕾，侯珂露，司霞，赵美，王文沛，刘思鲁，黄琳，刘盈，封宇飞 |
| AUTHORS： | LIU Yi，LIANG Xinyu，SONG Jiawei，LIU Yue，HU Lei，HOU Kelu，SI Xia，ZHAO Mei，WANG Wenpei，LIU Silu，HUANG Lin，LIU Ying，FENG Yufei |
| 关键字： | Ⅰ类切口手术；骨科；抗菌药物；合理用药；层次分析法；逼近理想解排序法 |
| KEYWORDS： | Type Ⅰ incision；Orthopedic department ；Antibiotics；Rational drug use ；Analytic hierarchy process ；TOPSIS |
| 阅读数： | 273 次 |
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