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EQ-5D-5L新增认知维度用于贵州农村人群的效果及其价值探索
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| 篇名： | EQ-5D-5L新增认知维度用于贵州农村人群的效果及其价值探索 |
| TITLE： | Exploration on the effects and value of new cognitive dimension of EQ- 5D-5L in rural population of Guizhou |
| 摘要： | 目的 为准确测量人群健康现状、开展药物经济学评价和指导卫生资源配置提供参考。方法采用配额及方便抽样法，于2020年7－9月在贵州省六枝特区、黔西市、剑河县下辖农村中各抽取5个行政村，基于全国人口普查结果中农村人群的性别和年龄比例配额抽取330例受访者进行问卷调查。问卷内容包括含社会人口学特征及一般健康信息的自制量表、增加了认知维度（包括注意力、记忆力、计算能力和学习能力）的五水平欧洲五维健康量表（EQ-5D-5L）（以下称为“新增维度量表”）及简易智能精神状态检查（MMSE）量表。考察新增维度量表的信度、效度和新增维度对受访者生命质量的影响，验证其测量特性，并探讨其在开展药物经济学评价及指导卫生资源配置中的应用价值。结果研究共发放问卷330份，回收问卷320份，均为有效问卷，回收率与有效率分别为96.97％、100％。新增维度量表的天花板效应为13.44％、分半信度系数为0.821、总体Cronbach’sα系数为0.852；探索性因子分析结果显示，新增维度量表可加载于生理、认知、心理3个因子，累计贡献率为69.35％；新增维度与MMSE量表维度的相关系数为0.19～0.61，呈中度或中至强相关（P＜0.01）。相比EQ-5D-5L，新增各维度后回归模型的解释能力提高了5.00％～17.50％。结论新增维度量表可行性高、信效度良好，显著降低了EQ-5D-5L的天花板效应，对人群生命质量的测评敏感度更高，能够更好地测评农村人群的生命质量。建议可将其应用于生命质量评价、干预措施效果分析及相关经济性评价中。 |
| ABSTRACT： | OBJECTIVE To provide re ference for accurate measurem ent of population health status ，pharmacoeconomic evaluation and guidance of health resource allocation. METHODS Using quota and convenient sampling ，five administrative villages were selected from the rural areas under the jurisdiction of Liuzhi special zone ，Qianxi city and Jianhe county of Guizhou province from July to September 2020. Based on the gender and age ratio quota of rural population in the results of the national census，330 respondents were selected for questionnaire survey. The contents of the questionnaire included the self-made scale containing sociodemographic characteristics and general health information ，five-level EuroQoL five-dimension questionnaire （EQ-5D-5L，hereinafter referred to as the “new dimension scale ”）with cognitive dimensions （including attention ，memory， computing ability and learning ability ）and mini-mental state examination （MMSE）. The effects of reliability ，validity and new dimensions of new dimension scale on respond ents’quality of life were investigate ，and its measurement characteristics were verified；the application value of it in pharmacoeconomic hy_cheer@126.com evaluation and guiding the allocation of health resources were explored. RESULTS A total of 330 questionnaires weredistributed，320 were recovered and 320 were effective. The recovery rate and effective rate were 96.97％ and 100％ respectively. The ceiling effect of new dimension scale was 13.44％，the split-half reliability was 0.821，and the overall Cronbach ’s α was 0.852. Exploratory factor analysis showed that the new dimension scale was loaded with physiological ，cognitive and psychological factors ，and the cumulative contribution rate was 69.35％. The correlation coefficient between the new dimension and the dimension of MMSE scale were 0.19-0.61，showing a moderate or medium to strong correlation （P＜0.01）. Compared with EQ- 5D-5L，after adding each dimension ，the interpretation ability of the regression model was improved by 5.00％-17.50％. CONCLUSIONS The new dimension scale has high feasibility ，good reliability and validity ，significantly reduces the ceiling effect of EQ- 5D-5L，has higher sensitivity to the evaluation of people ’s quality of life，and can better evaluate the quality of life of rural population. It is suggested that it can be applied for quality of life evaluation，intervention effect analysis and related economic evaluation. |
| 期刊： | 2022年第33卷第02期 |
| 作者： | 黄艳，伍红艳，杨智豪，罗南，王龙，林枭，郝兴敏 |
| AUTHORS： | HUANG Yan，WU Hongyan ，YANG Zhihao ，LUO Nan，WANG Long，LIN Xiao，HAO Xingmin |
| 关键字： | 五水平欧洲五维健康量表；认知；生命质量；农村人群；药物经济学 |
| KEYWORDS： | five-level EuroQoL five-dimensional questionnaire ；cognition；quality of life ；rural population ；pharmacoeconomics |
| 阅读数： | 289 次 |
| 本月下载数： | 2 次 |
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