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WHO儿童基本药物示范目录、WHO和我国基本药物目录中抗感染药物的比较与启示
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| 篇名： | WHO儿童基本药物示范目录、WHO和我国基本药物目录中抗感染药物的比较与启示 |
| TITLE： | Comparison and enlightenment of anti-infective medicines between WHO model list of essential medicines for children，essential medicine list of WHO and national essential medicine list |
| 摘要： | 目的 为丰富我国儿童抗感染药物用药选择、促进我国儿童基本药物目录的建立提供建议和参考。方法采用描述性分析法，从药物类别、品种、剂型、规格和符号标记等方面对比研究《WHO儿童基本药物示范目录》（EMLc）、《WHO基本药物目录》（EML）与我国《国家基本药物目录》（NEML）中抗感染药物的异同。结果EMLc中的抗感染药物均被EML覆盖（占EML的85.3%）。NEML中抗感染药物的药物信息相对欠缺，新品种较少，如未收录EMLc中第三代及以上头孢菌素，剂型也相对局限（主要为片剂、胶囊和注射剂），但规格较为丰富。结论参考EMLc，从年龄、体质量、联合用药等方面增加我国基本药物的儿童用药指导，增加NEML中口服液体制剂、刻痕片等儿童适用剂型；在更新NEML时纳入头孢克肟、达卡他韦等儿童适宜的较新品种；参照EML与EMLc的承接性，基于NEML建立我国儿童基本药物目录，以满足儿童用药需求，促进儿童药物安全使用。 |
| ABSTRACT： | OBJECTIVE To provide suggestions and reference for enriching the selection of anti-infective medicines for children in China and promoting the establishment of the Essential Medicine List for Children in China. METHODS Descriptive analysis method was used to statistically compare the differences and similarities of anti-infective medicines included in the World Health Organization Model List of Essential Medicines for Children （EMLc）， World Health Organization Model List of Essential Medicines （EML） and National Essential Medicine List （NEML） in terms of drug category， variety， dosage form， specification， symbol mark， etc. RESULTS All anti-infective medicines of EMLc were covered by EML （85.3%）. NEML lacked the information of anti-infective medicines relatively， and contained few new categories； for example， the third-generation and above cephalosporins in EMLc were not included， and the drug dosage forms were also relatively limited （mainly tablets， capsules and injections）， but the specifications were relatively rich. CONCLUSIONS With reference to EMLc， the guidance on the use of essential medicines for children in China should be added from the aspects of age， body weight， combined medication， etc.， and the dosage forms suitable for children such as oral liquid preparations and scored tablets should be added to NEML； when updating the NEML the newer drugs suitable for children such as cefixime and dacatavir should be included. Finally， with reference to the continuity of EML and EMLc， the Essential Medicine List for Children in China should be established based on NEML to meet the drug needs of children and promote the safe use of drugs in children. |
| 期刊： | 2023年第34卷第11期 |
| 作者： | 董途；马鑫；马姝丽；刘伟 |
| AUTHORS： | DONG Tu，MA Xin，MA Shuli，LIU Wei |
| 关键字： | 抗感染药物；基本药物目录；儿童用药；世界卫生组织 |
| KEYWORDS： | anti-infective medicines； Essential Medicine List； medicine use of children； WHO |
| 阅读数： | 147 次 |
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