我院免疫抑制剂超说明书用药情况分析
x

请在关注微信后,向客服人员索取文件

篇名: 我院免疫抑制剂超说明书用药情况分析
TITLE:
摘要: 目的:提高免疫抑制剂合理用药水平。方法:介绍我院免疫抑制剂超说明书用药现状,主要包括超适应证用药、超适应年龄组用药、超联合用药,并查找相关依据,分析其使用的有效性、安全性和合理性。结果与结论:免疫抑制剂超说明书用药需要有科学、合理的依据,以患者利益为考量,在病情需要且结合了患者知情同意的情况下可以适当合理地超说明书用药,但要定期监测患者血药浓度等实验室指标及不良反应情况,根据临床表现调整用药方案。
ABSTRACT: OBJECTIVE: To explore how to avoid the risks of immunosuppressant off-label uses. METHODS: The situation of immunosuppressant off-label uses was introduced in our hospital, mainly including over indication drug use, over age drug use, over drug combination. Related reference were checked to analyze the effectiveness, safety and reasonability. RESULTS&CONCLUSIONS: Immunosuppressant off-label use needs scientific and reasonable basis. In consideration of patients’ interests and medical necessity, off-label drug use could be carried out appropriately and reasonably in situations where patients are aware of the risks and consent. However, laboratory index, like blood concentration, and adverse reactions should be monitored at regular intervals, therapeutic regimens are supposed to be adjusted based on clinical manifestation.
期刊: 2016年第27卷第2期
作者: 廖靖萍,于西全,宋洪涛
AUTHORS: LIAO Jingping,YU Xiquan,SONG Hongtao
关键字: 免疫抑制剂;超说明书用药;风险;血药浓度;不良反应
KEYWORDS: Immunosuppresant; Off-label drug uses; Risk; Blood concentration; ADR
阅读数: 367 次
本月下载数: 6 次

* 注:未经本站明确许可,任何网站不得非法盗链资源下载连接及抄袭本站原创内容资源!在此感谢您的支持与合作!