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5 640例门诊患者生殖道支原体属感染状况及耐药率分析
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| 篇名： | 5 640例门诊患者生殖道支原体属感染状况及耐药率分析 |
| TITLE： | |
| 摘要： | 目的：为玉林地区门诊患者生殖道支原体属感染合理使用抗菌药物提供参考。方法：采用一体化培养板，对我院2012－2014年19 836例门诊疑似生殖道感染患者生殖道分泌物进行测定，并对药敏试验结果进行统计分析。结果：19 836份标本中，支原体属感染阳性标本5 640例，阳性率28.4％；其中，解脲脲原体（Uu）、人型支原体（Mh）和混合（Uu+Mh）感染分别占88.0％、3.8％和8.2％。男性患者支原体属阳性率低于女性患者（P＜0.05），其中男、女性患者检出率最多的年龄段分别在25～40岁（81.3％）和20～35岁（78.6％）。各年度中，支原体属对9种抗菌药物耐药率有不同程度的差异。总的来说，Uu对林可霉素耐药率接近100％，Mh对红霉素、罗红霉素和阿奇霉素耐药率均＞70％，Uu+Mh则仅对交沙霉素、米诺环素和多西环素耐药率＜10％。结论：2012－2014年，玉林地区门诊男女患者生殖道支原体属感染率逐年增长，以Uu感染为主，耐药严重，还应注意Mh及混合感染的增多。交沙霉素、米诺环素和多西环素可以作为经验性治疗的首选药物，其他药物则应参照药敏结果合理使用。 |
| ABSTRACT： | OBJECTIVE： To provide reference for the rational use of antibiotics in outpatients who had genital tract Mycoplasma infections in Yulin area. METHODS： Using the integration culture plate，19 836 outpatient’s specimens with suspected Mycoplasma infection from Yulin Maternal and Child Health Care Hospital during 2012 to 2014 were tested， and then the results of drug susceptibility test were retrospectively analyzed. RESULTS： In the total of 19 836 inspected specimens， 5 640 cases were positive with the rate of 28.4％. The positive rate of Ureaplasma urealyticum（Uu）， Mycoplasma hominis（Mh）， mixed（Uu+ Mh） infection were 88.0％， 3.8％ and 8.2％ respectively. The positive rate of male patient with Mycoplasma infection was lower than female patient（P＜0.05）. Male and female patients with positive maximum age respectively at the age of 25 to 40 （81.3％） and 20 to 35 years old （78.6％）. From 2012 to 2014， Mycoplasma showed different degree of drug resistance to 9 kinds of antibiotics. In general， the resistance rate of Uu to lincocin was close to 100％， Mh to erythromycin， roxithromycin and azithromycin were higher than 70％， and those of Uu+Mh were lower than 10％ only to josamcine， minocycline and doxycycline. CONCLUSIONS： During 2012 to 2014， the rate of genital tract Mycoplasma infection in male and female outpatients of Yulin region increased year by year， and the infection mainly caused by Uu with a serious drug resistance. We should also pay attentions to the increase of Mh infection and mixed infection. Josamycin， minocycline and doxcycline can be used as a drug choice for empiric preferred treatment， and other antibiotics should be used based on antibiotics susceptibility test results. |
| 期刊： | 2016年第27卷第5期 |
| 作者： | 郑新，李岸英，刘忠，卢安妮，王浩龙，庞琨 |
| AUTHORS： | ZHENG Xin，LI Anying，LIU Zhong，LU Anni，WANG Haolong，PANG Kun |
| 关键字： | 支原体属；解脲脲原体；人型支原体；生殖道感染；耐药率；门诊患者 |
| KEYWORDS： | Mycoplasma； Ureaplasma urealyticum； Mycoplasma hominis； Genital tract infection； Drug resistance； Outpatient |
| 阅读数： | 301 次 |
| 本月下载数： | 1 次 |
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