肿瘤患者化疗用药合理性调查及药学监护
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篇名: 肿瘤患者化疗用药合理性调查及药学监护
TITLE:
摘要: 目的:为规范肿瘤患者化疗用药提供参考,并探讨其药学监护要点。方法:选取山东省4家三级甲等医院肿瘤化疗病历2 242份,调查化疗用药方案和药学监护情况,并对不合理用药原因进行分析,总结临床药学监护要点。结果:化疗用药不合理1 295例,其中给药剂量不合理占26.87%,止吐药物不合理占14.44%,方案选择不合理占13.13%,药物选择不合理占10.89%,给药顺序不合理占10.04%。总结出6项化疗合理用药监护指标,即方案选择合理性、药物选择合理性、药物剂量合理性、给药时间和顺序合理性、溶剂浓度和途径合理性、辅助用药合理性,覆盖了肿瘤患者化疗用药全程。结论:通过对肿瘤患者化疗用药合理性的调查来规范用药过程的药学监护,有利于提高临床药师药学服务水平,促进临床合理用药。
ABSTRACT: OBJECTIVE: To provide reference for standardizing chemotherapy drug use in tumor patients, and to investigate the points of pharmaceutical care. METHODS: 2 242 medical records of tumor chemotherapy were sampled from 4 third grade class A hospitals to investigate chemotherapy drug plan and pharmaceutical care. The reasons for irrational drug use were analyzed, and the points of pharmaceutical care were summarized. RESULTS: There were 1 295 cases of irrational chemotherapy drug use, among which irrational dose accounted for 26.87%; irrational antiemetic drugs use 14.44%; irrational chemotherapy plan 13.13%; irrational drug selection 10.89%; irrational dosing order 10.04%. 6 items of rational chemotherapy drug use monitoring index were summarized, which were rationality of scheme selection, drug selection, drug dose, dosing time and order, solvent concentration, route of administration, adjuvant drug use; covering the process of chemotherapy. CONCLUSIONS: Pharmaceutical care can be standardized through rationality investigation on chemotherapy drug use of tumor patients, which contributes to improving pharmaceutical care level of clinical pharmacists, and rational drug use the clinic.  
期刊: 2016年第27卷第5期
作者: 蒲兵,孙波,谢法东
AUTHORS: PU Bing,SUN Bo,XIE Fadong
关键字: 抗肿瘤药物;化疗;临床药师;药学监护;合理用药
KEYWORDS: Antitumor drug; Chemotherapy; Clinical pharmacist; Pharmaceutical care; Rational drug use
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