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我院门诊2013－2015年抗消化道溃疡药使用分析
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| 篇名： | 我院门诊2013－2015年抗消化道溃疡药使用分析 |
| TITLE： | |
| 摘要： | 目的：为抗消化道溃疡药的临床合理使用提供参考。方法：回顾性分析我院门诊2013－2015年抗消化道溃疡药使用情况，包括药品名称、销售金额、用药频度（DDDs）、日均费用（DDC）、单/多病处方、疗效和处方合理性等。结果：我院门诊2013－2015年共使用8种抗消化道溃疡药，其中奥美拉唑胶囊和雷贝拉唑胶囊销售金额和DDDs增长较快，且DDC较高，其余药品基本稳定。单病处方抑酸药使用率低于多病处方，而抗酸药使用率高于多病处方，差异均有统计学意义（P＜0.05）。我院门诊2013－2015年消化道溃疡患者治疗总有效率由77.98％逐年提高至82.68％， 2015年与2013年比较差异有统计学意义（P＜0.05）；不合理处方率由5.01％逐年下降至2.12％，各年间比较，差异均有统计学意义（P＜0.05）。结论：我院门诊抗消化道溃疡药治疗总体疗效较好，首选奥美拉唑，但是处方中仍然存在一定的不合理情况，需引起临床医师的重视。 |
| ABSTRACT： | OBJECTIVE： To provide reference for rational use of drugs for gastrointestinal ulcer. METHODS： The drug use for gastrointestinal ulcer in outpatient department of our hospital during 2013-2015 was analyzed retrospectively in respects of drug name， consumption sum， DDDs， DDC， single/multiple diseases prescription， therapeutic efficacy， rationality of presoription， etc. RESULTS： A total of 8 kinds of drugs use for gastrointestinal ulcer in outpatient department of our hospital during 2013-2015， among which the consumption sum and DDDs of Omeprazole capsule and Rabeprazole capsule increased rapidly， and their DDC were the higher others； those of other drugs kept stable. The proportion of acid-inhibitory drugs in single disease prescriptions was lower than in multiple diseases prescriptions， while that of antiacid was higher than in multiple diseases prescriptions， with statistical significance （P＜0.05）. The total effective rate of patients with gastrointestinal ulcer gradually increased from 77.98％ to 82.68％ in outpatient department of our hospital during 2013-2015， there was statistical significance between 2015 and 2013 （P＜0.05）； the proportion of irrational prescriptions decreased from 5.01％ to 2.12％ year by year， with statistical significance among those years （P＜0.05）. CONCLUSIONS： Omeprazole is the first choice for gastrointestinal ulcer in outpatient department of our hospital with good therapeutic efficacy. There still are some irrational drug use in prescriptions， and clinicians should pay attention to those situations. |
| 期刊： | 2016年第27卷第20期 |
| 作者： | 何灿丽，黄东慧，张玉芳 |
| AUTHORS： | HE Canli，HUANG Donghui，ZHANG Yufang |
| 关键字： | 消化道溃疡；销售金额；用药频度；疗效；处方合理性；用药分析 |
| KEYWORDS： | Gastrointestinal ulcer； Consumption sum； DDDs； Therapeutic efficacy； Rationality of presoription； Analysis of drug use |
| 阅读数： | 349 次 |
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