不同操作方法对多西他赛药物残留量的影响-中国药房

不同操作方法对多西他赛药物残留量的影响

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篇名：	不同操作方法对多西他赛药物残留量的影响
TITLE：
摘要：	目的：探讨不同操作方法对多西他赛药物残留量的影响。方法：选取多西他赛注射液60支，A组（30支）采用按说明书要求的标准操作方法，B组（30支）采用临床通用的常用操作方法，分别放置5、10、15 min抽取药液后收集残留液，计算药物残留量，比较因操作配制方法、放置时间不同所产生的残留量差别。结果：在放置5、10、15 min 时， B组的平均残留液体积及药物残留量均高于A组（P＜0.05）。同组内比较，放置10、15 min时平均残留液体积及药物残留量均低于放置5 min者（P＜0.05或P＜0.01），且放置15 min时平均残留液体积及药物残留量也均低于放置10 min者（P＜0.05）。结论：调配人员的规范操作对减少多西他赛残留量，保证患者安全、有效、足量的用药至关重要。建议临床工作者按标准操作规程操作。
ABSTRACT：	OBJECTIVE： To investigate the effects of different operation methods on the residual amount of docetaxel. METHODS： 60 Docetaxel injections were selected and divided into two groups， i.e. standard operation method was adopted in group A （30 injections）， and clinical common operation method was used in group B （30 injections）. Docetaxel injections were placed for 5， 10 or 15 minutes respectively， and drained. Residual liquid was collected to calculate residual amount. The difference of residual amount， due to preparation method and standing time， were compared between two groups. RESULTS： After placing for 5， 10 or 15 min， the volume and amount of residual liquid in group B were significantly higher than in group A （P＜0.05）. In same group， the volume and amount of residual liquid after placing for 10 and 15 min were all lower than that after placing for 5 min （P＜0.05 or P＜0.01）； the volume and amount of residual liquid after placing for 15 min were lower than that after placing for 10 min （P＜0.05）. CONCLUSIONS： The standard operation of pharmacy dispensing staff is very important to reduce the residual amount of docetaxel， and guarantee safe， effective and sufficient medication. It is suggested that clinical staff should abide by standard operation method.
期刊：	2016年第27卷第1期
作者：	张惠霞，周珺，李茂星，贾正平
AUTHORS：	ZHANG Huixia，ZHOU Jun，LI Maoxing，JIA Zhengping
关键字：	多西他赛注射液；残留量；操作方法
KEYWORDS：	Docetaxel injection； Residual amount； Operation method
阅读数：	525 次
本月下载数：	6 次

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