上海地区22家医院2013-2015年带状疱疹患者药物应用分析
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篇名: | 上海地区22家医院2013-2015年带状疱疹患者药物应用分析 |
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摘要: | 目的:了解上海地区22家医院带状疱疹患者的药物应用情况及趋势,为临床合理用药提供参考。方法:对上海地区22家医院2013-2015年带状疱疹患者使用药物的人次占比、销售金额、用药频度(DDDs)、日均费用(DDC)等数据进行统计分析。结果:带状疱疹多发于成人,集中于45岁以上人群(>75%)。神经营养药、抗疱疹病毒药、抗神经痛药使用人次占比排在前3位,局部治疗药、免疫调节药及糖皮质激素亦占一定比例。抗病毒药中,伐昔洛韦各年度的销售金额和DDDs均列第1位,溴夫定的DDC最高;抗神经痛药中,使用人次占比最高的是抗癫痫药(13.78%),其复合增长率也最高(30.77%),其中使用人次最多的药品为加巴喷丁;神经营养药中,使用人次占比最高的是甲钴胺(32.98%);免疫调节药中,胸腺法新的使用人次最多,可能存在不合理应用情况。结论:上海地区带状疱疹药物治疗方案基本符合相关治疗指南,但免疫调节药的不合理应用等问题仍需引起关注并进行监管。 |
ABSTRACT: | OBJECTIVE: To investigate the utilization and trend of drugs for herpes zoster patients from 22 hospitals of Shanghai area, and to provide reference for rational use of drugs. METHODS: The utilization of drugs for herpes zoster patients from 22 hospitals of Shanghai area during 2013-2015 was analyzed statistically in respects of proportion of patients, consumption sum, DDDs, DDC, etc. RESULTS: Herpes zoster was more likely to occur in adults, mostly in more than 45 year-old group (>75%). The proportions of patients of neurotrophic antivirals, anti-herpes virus and acesodyne drugs ranked in the top three. Topical, immunomodulatory and glucocorticoid drugs accounted for a certain proportion. Among antivirals, the consumption sum and DDDs of valaciclovir ranked the first place, and DDC of brivudine was the highest. Among acesodyne, the proportions of patients of antiepileptic drugs was the highest (13.78%), and its compound growth rate was also the highest (30.77%); the number of patients of gabapentin was the largest. Among neurotrophic drugs, the proportions of patients of mecobalamine was the highest (32.98%). Among immunomodulatory drugs, the number of patients of thymalfasin was the largest, which may be irrational. CONCLUSIONS: The treatment of herpes zoster in Shanghai area is basically in accordance with the guidelines. The irrational use of immunomodulatory drugs should be paid attention to and supervised. |
期刊: | 2017年第28卷第8期 |
作者: | 李莹,陈中建 |
AUTHORS: | LI Ying,CHEN Zhongjian |
关键字: | 带状疱疹;用药分析;合理用药;上海地区 |
KEYWORDS: | Herpes zoster; Analysis of drug use; Rational drug use; Shanghai area |
阅读数: | 458 次 |
本月下载数: | 9 次 |
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