我院2013-2015年住院患者抗凝血药应用合理性分析
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篇名: 我院2013-2015年住院患者抗凝血药应用合理性分析
TITLE:
摘要: 目的:为抗凝血药临床合理使用提供参考。方法:从医院信息系统提取我院2013-2015年住院患者抗凝血药使用的医嘱信息,计算和分析该类药品的销售金额、用药频度(DDDs)、日均费用(DDC)以及各科室使用情况。结果:2013-2015年,低分子肝素钙注射液(6 000 AXaIU)、依诺肝素钠注射液(6 000 AXaIU)、达肝素钠注射液(5 000 IU)和利伐沙班片(10 mg)的金额比呈上升趋势,那屈肝素钙注射液(6 150、4 100 AXaIU)和磺达肝癸钠注射液(2.5 mg)的金额比呈下降趋势。那屈肝素钙注射液(4 100 AXaIU)、达肝素钠注射液(5 000 IU)和依诺肝素钠注射液(6 000 AXaIU)的DDDs位居前3位。利伐沙班片的DDC值最高,为167.60~180.25元。那屈肝素钙注射液(6 150 、4 100 AXaIU)、低分子肝素钙注射液(6 000 AXaIU)、磺达肝癸钠注射液(2.5 mg)和华法林钠片(3 mg)3年内使用同步性较好,B/A值为0.50~1.50。血管外科的利伐沙班销售金额及使用率均居第1位。结论:结合医院疾病谱及各种药品的特点和不良反应,我院近3年抗凝血药使用趋于合理,但其使用情况仍应作为常规药学监测内容。
ABSTRACT: OBJECTIVE: To provide reference for rational use of anticoagulant drugs in the clinic. METHODS: Medical orders of anticoagulant drugs were collected from hospital information system of our hospital during 2013-2015. Those medical orders were analyzed in respects of consumption sum, DDDs, DDC and drug utilization. RESULTS: During 2013-2015, the sum tatio of Low-molecular-weight heparins calcium injection(6 000 AXaIU),Enoxaparin sodium injection(6 000 AXaIU), Dalteparin sodium injection(5 000 IU) and Rivaroxaban tablets(10 mg)were on the rise,while those of Nadroparin calcium infection(6 150, 4 100 AXaIU) and Fondaparinux sodium injection(2.5 mg) were in the decline. DDDs of Nadroparin calcium injection (4 100 AXaIU), Dalteparin sodium injection (5 000 IU) and Enoxaparin sodium injection (6 000 AXaIU) took up the first 3 places. DDC of Rivaroxaban tablets was the highest, being 167.60-180.25 yuan. The utilization of Nadroparin calcium injection(6 150, 4 100 AXaIU),Low-molecular-weight heparins calcium injection (6 000 AXaIU), Fondaparinux sodium injection(2.5 mg) and Warfarin sodium tablets(3 mg) showed good synchronization within 3 years, and the values of B/A ranged 0.50-1.50. Both consumption sum and utilization rate of rivaroxaban took up the first place in vascular surgery department. CONCLUSIONS: Based on the spectrum of diseases, the features of drugs and ADR, the utilization of anticoagulant drugs in our hospital is rational during recent 3 years. However, the utilization of anticoagulant drugs should be still used as routine pharmaceutical monitoring content.
期刊: 2017年第28卷第14期
作者: 李丽莉,鄢丹,田宗梅,顾红燕
AUTHORS: LI Lili,YAN Dan,TIAN Zongmei,GU Hongyan
关键字: 抗凝血药;低分子肝素;利伐沙班;合理用药
KEYWORDS: Anticoagulant drugs; Low-molecular-weight heparins; Rivaroxaban; Rational use of drug
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