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细胞毒性药品打包袋的研制及应用
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| 篇名： | 细胞毒性药品打包袋的研制及应用 |
| TITLE： | |
| 摘要： | 目的：加强静脉药物调配中心（PIVAS）工作人员的职业防护，确保药品运送的安全、及时。方法：用牛津布、丝绒棉、珍珠棉、硅胶、活性炭、绳等材料制作细胞毒性药品打包袋。以注射用紫杉醇脂质体为例考察打包袋的应用效果。选取PIVAS调配的注射用紫杉醇脂质体医嘱156份，按随机数字表法分为试验组和对照组，各78份。试验组调配药品使用细胞毒性药品打包袋进行打包，对照组使用原有塑料打包袋进行打包。比较两组药品的打包时间、运送时间、渗漏和碎瓶情况、破损处理时间、损耗金额等。结果：两组调配药品的运送时间比较，差异无统计学意义（P＞0.05）；而试验组打包时间显著长于对照组；对照组渗漏16瓶、碎瓶8瓶，试验组渗漏且非溢出（渗在硅胶层）3瓶，无碎瓶情况发生；试验组的破损处理时间显著短于对照组，损耗金额显著少于对照组，差异均有统计学意义（P＜0.05）。结论：本研究所研制的细胞毒性药品打包袋可起到防溢、抗震作用，降低了药品损耗，同时还加强了医护人员的职业安全防护。 |
| ABSTRACT： | OBJECTIVE： To strengthen the occupational protection of pharmacy intravenous admixture service （PIVAS） staff， and to ensure the safe and timely delivery of drugs. METHODS： The cytotoxic drug packing bag was made by oxford cloth， velvet cotton， pearl cotton， silica gel， activated carbon， rope， etc. Taking Paclitaxel liposomes for injection as an example， the application effect of packing bags was observed. A total of 156 medical orders of PIVAS formulated Paclitaxel liposomes for injection were selected and divided into test group and control group aoccording to random number table. The dispensing drugs were packed with cytotoxic drug packing bag in trial group， and packed with previous plastic packing bag in control group. The packing time of each drug， the delivery time， leaking and shattering， the breakage processing time and loss amount were compared between 2 groups. RESULTS： There was no statistical significance in the delivery time between 2 groups （P＞0.05）. The packing time of trial group was significantly longer than control group； there were 16 bottles of leaking in the control group， and 8 bottles of shattering； In trial group， 3 bottles were leaking but not spilled over （infiltrated in the silica gel layer）， and there was no shattering bottle； the breakage processing time of trial group was significantly shorter than that of control group； the loss amount was significantly less than that of control group， with statistical significance （P＜0.05）. CONCLUSIONS： The cytotoxic drug packaging bag developed in this study can play a spill-proof， anti-seismic role， reduce the loss of valuable drugs， and also strengthen the occupational safety and health protection of medical staff. |
| 期刊： | 2018年第29卷第4期 |
| 作者： | 刘晓晨，刘丽，张立芬，肇东薇，董梅 |
| AUTHORS： | LIU Xiaochen，LIU Li，ZHANG Lifen，ZHAO Dongwei，DONG Mei |
| 关键字： | 细胞毒性药品；打包袋；静脉药物调配中心；职业防护 |
| KEYWORDS： | Cytotoxic drug； Packing bag； Pharmacy intravenous admixture service； Occupational protection |
| 阅读数： | 353 次 |
| 本月下载数： | 14 次 |
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