我院头孢菌素类注射剂皮试费用的经济学分析
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篇名: 我院头孢菌素类注射剂皮试费用的经济学分析
TITLE:
摘要: 目的:为我院头孢菌素类注射剂皮试的规范化管理提供依据。方法:采用回顾性分析方法,统计出2015年9月1日-2016年8月31日我院常用的8种头孢菌素类[头孢硫脒(1.0 g)、头孢硫脒(0.5 g)、头孢替安(1.0 g)、头孢替安(0.5 g)、头孢他啶(0.5 g)、头孢米诺(0.5 g)、头孢米诺(1.0 g)、头孢曲松(1.0 g)]注射剂的皮试情况、皮试相关成本以及由于头孢菌素类注射剂过敏反应所产生的相关费用,并对头孢菌素类注射剂皮试成本与通过皮试减少的过敏反应成本进行比较。结果:有100 330例患者使用过上述8种头孢菌素类注射剂,皮试率为82.49%,皮试阳性率为6.27%;皮试直接成本为3 434 411.72元,间接成本为141 985.12元;患者承担的费用为3 162 901.44元,医保承担的费用为259 096.28元,全社会承担的费用为3 576 396.84元。从全社会角度分析,8种头孢菌素类注射剂的平均皮试成本为(447 049.61±247 395.07)元,通过皮试减少的过敏反应平均成本为(316 075.48±260 600.49)元,皮试成本明显高于通过皮试所减少的过敏反应成本,差异有统计学意义(P<0.05)。结论:头孢菌素类注射剂的皮试阳性率低、成本高。国家应对此进行规范化管理,在保证用药安全的前提下,减少患者的经济负担。
ABSTRACT: OBJECTIVE: To provide reference for standardized management of skin test of cephalosporin injection in our hospital. METHODS: In retrospective analysis, skin test of 8 kinds of cephalosporin [cefotaxime (1.0 g), cefotaxime (0.5 g), cefotiam (1.0 g), cefotiam (0.5 g), ceftazidime (0.5 g), cefminox (0.5 g), cefminox (1.0 g), ceftriaxone (1.0 g)] and the cost of skin test, related cost of allergic reaction induced by cephalosporin injection were analyzed statistically during Sept. 1st, 2015-Aug. 31th, 2016. The cost of skin test of cephalosporin injection was compared with allergic reaction cost reduced by skin test. RESULTS: The positive rate of 100 330 patients who used above 8 kinds of cephalosporin injections was 6.27%; the rate of skin test was 82.49%; the direct cost of skin test was 3 434 411.72 yuan; the indirect cost was 141 985.12 yuan; the cost of patient was 3 162 901.44 yuan; the cost of medical insurance was 259 096.28 yuan; the cost of the whole society was 3 576 396.84 yuan. From the perspective of the whole society, the cost of skin test of cephalosporin injections was (447 049.61±247 395.07) yuan, and allergic reaction cost reduced by skin test was (316 075.48±260 600.49)yuan. The cost of skin test was significantly higher than allergic reaction cost reduced by skin test, with statistical significance (P<0.05). CONCLUSIONS: Skin test of cephalosporin injection is low in positive rate, has high expense. The government standardizes the management of skin test of cephalosporin injection and reduces the economic burden of patients under the premise of ensuring the safety of drug use.
期刊: 2017年第28卷第14期
作者: 张丽霄,杨翠翠,付俊涛,汪新茹,张丽珍,杜书章
AUTHORS: ZHANG Lixiao,YANG Cuicui,FU Juntao,WANG Xinru,ZHANG Lizhen,DU Shuzhang
关键字: 头孢菌素;注射剂;皮试;药物经济学;过敏反应
KEYWORDS: Cephalosporin; Injection; Skin test; Pharmacoeconomics; Allergic reaction
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